Través PG, Pimentel-Santillana M, Carrasquero LM, Pérez-Sen R, Delicado EG, Luque A, Izquierdo M, Martín-Sanz P, Miras-Portugal MT, Boscá L. Selective Impairment of P2Y Signaling by Prostaglandin E2 in Macrophages: Implications for Ca2+-Dependent Responses. J Immunol 2013; 190(8):4226-35. doi: 10.4049/jimmunol.1203029. Epub 2013 Mar 11.

Engel T, Jiménez-Pacheco A, Miras-Portugal MT, Diaz-Hernandez M, Henshall DC. P2X7 receptor in epilepsy; role in pathophysiology and potential targeting for seizure control. Int J Physiol Pathophysiol Pharmacol. 2012;4(4):174-87. Epub 2012 Dec 26.

García-Huerta P, Díaz-Hernandez M, Delicado EG, Pimentel-Santillana M, Miras-PortugalMT, Gómez-Villafuertes R. The specificity protein factor Sp1 mediates transcriptional regulation of P2X7 receptors in the nervous system.J Biol Chem. 2012 Dec 28;287(53):44628-44. doi: 10.1074/jbc.M112.390971. Epub 2012 Nov 8.

Guzman-Aranguez A, Díez LM, Martín-Gil A, Gualix J, Miras-Portugal MT, Pintor J. Effect of diinosine polyphosphates on intraocular pressure in normotensive rabbits. Exp Eye Res. 2012 Aug;101:49-55. doi: 10.1016/j.exer.2012.05.011. Epub 2012 Jun 4.

del Puerto A, Díaz-Hernández JI, Tapia M, Gomez-Villafuertes R, Benitez MJ, Zhang J, Miras-Portugal MT, Wandosell F, Díaz-Hernández M, Garrido JJ. Adenylate cyclase 5 coordinates the action of ADP, P2Y1, P2Y13 and ATP-gated P2X7 receptors on axonal elongation. J Cell Sci. 2012 Jan 1;125(Pt 1):176-88. doi: 10.1242/jcs.091736. Epub 2012 Jan 16.

Engel T, Gomez-Villafuertes R, Tanaka K, Mesuret G, Sanz-Rodriguez A, Garcia-Huerta P, Miras-Portugal MT, Henshall DC, Diaz-Hernandez M. Seizure suppression and neuroprotection by targeting the purinergic P2X7 receptor during status epilepticus in mice. FASEB J. 2012 Apr;26(4):1616-28. doi: 10.1096/fj.11-196089. Epub 2011 Dec 23.

Diaz-Hernandez JI, Gomez-Villafuertes R, León-Otegui M, Hontecillas-Prieto L, Del Puerto A, Trejo JL, Lucas JJ, Garrido JJ, Gualix J, Miras-Portugal MT, Diaz-Hernandez M. In vivo P2X7 inhibition reduces amyloid plaques in Alzheimer's disease through GSK3β and secretases. Neurobiol Aging. 2012 Aug;33(8):1816-28. doi: 10.1016/j.neurobiolaging.2011.09.040. Epub 2011 Nov 1.

Tomás-Zapico C, Díez-Zaera M, Ferrer I, Gómez-Ramos P, Morán MA, Miras-Portugal MT, Díaz-Hernández M, Lucas JJ. α-Synuclein accumulates in huntingtin inclusions but forms independent filaments and its deficiency attenuates early phenotype in a mouse model of Huntington's disease. Hum Mol Genet. 2012 Feb 1;21(3):495-510. doi: 10.1093/hmg/ddr507. Epub 2011 Nov 1.

León-Otegui M, Gómez-Villafuertes R, Díaz-Hernández JI, Díaz-Hernández M, Miras-Portugal MT, Gualix J. Opposite effects of P2X7 and P2Y2 nucleotide receptors on α-secretase-dependent APP processing in Neuro-2a cells. FEBS Lett. 2011 Jul 21;585(14):2255-62. doi: 10.1016/j.febslet.2011.05.048. Epub 2011 Jun 2.

Gutiérrez-Martín Y, Bustillo D, Gómez-Villafuertes R, Sánchez-Nogueiro J, Torregrosa-Hetland C, Binz T, Gutiérrez LM, Miras-Portugal MT, Artalejo AR. P2X7 receptors trigger ATP exocytosis and modify secretory vesicle dynamics in neuroblastoma cells. J Biol Chem. 2011 Apr 1;286(13):11370-81. doi: 10.1074/jbc.M110.139410. Epub 2011 Feb 3.

Díez-Zaera M, Díaz-Hernández JI, Hernández-Álvarez E, Zimmermann H, Díaz-Hernández M, Miras-Portugal MT. Tissue-nonspecific alkaline phosphatase promotes axonal growth of hippocampal neurons. Mol Biol Cell. 2011 Apr;22(7):1014-24. doi: 10.1091/mbc.E10-09-0740. Epub 2011 Feb 2.

Jiménez E, Zafra F, Pérez-Sen R, Delicado EG, Miras-Portugal MT, Aragón C, López-Corcuera B. P2Y purinergic regulation of the glycine neurotransmitter transporters. J Biol Chem. 2011 Mar 25;286(12):10712-24. doi: 10.1074/jbc.M110.167056. Epub 2011 Jan 18.

Courjaret R, Miras-PortugalMT, Deitmer JW. Purinergic modulation of granule cells. Cerebellum. 2012 Mar;11(1):62-70. doi: 10.1007/s12311-010-0196-3. Review.

Díaz-Hernández M, Gómez-Ramos A, Rubio A, Gómez-Villafuertes R, Naranjo JR, Miras-Portugal MT, Avila J. Tissue-nonspecific alkaline phosphatase promotes the neurotoxicity effect of extracellular tau. J Biol Chem. 2010 Oct 15;285(42):32539-48. doi: 10.1074/jbc.M110.145003. Epub 2010 Jul 15.

Espada S, Ortega F, Molina-Jijón E, Rojo AI, Pérez-Sen R, Pedraza-Chaverri J, Miras-Portugal MT, Cuadrado A. The purinergic P2Y(13) receptor activates the Nrf2/HO-1 axis and protects against oxidative stress-induced neuronal death. Free Radic Biol Med. 2010 Aug 1;49(3):416-26. doi: 10.1016/j.freeradbiomed.2010.04.031. Epub 2010 May 4.

Carrasquero LM, Delicado EG, Sánchez-Ruiloba L, Iglesias T, Miras-Portugal MT. Mechanisms of protein kinase D activation in response to P2Y(2) and P2X7 receptors in primary astrocytes. Glia. 2010 Jun;58(8):984-95. doi: 10.1002/glia.20980.

Ortega F, Pérez-Sen R, Morente V, Delicado EG, Miras-Portugal MT. P2X7, NMDA and BDNF receptors converge on GSK3 phosphorylation and cooperate to promote survival in cerebellar granule neurons. Cell Mol Life Sci. 2010 May;67(10):1723-33. doi: 10.1007/s00018-010-0278-x. Epub 2010 Feb 10.

Marín-García P, Sánchez-Nogueiro J, Diez A, León-Otegui M, Linares M, García-Palencia P, Bautista JM, Miras-Portugal MT. Altered nucleotide receptor expression in a murine model of cerebral malaria. J Infect Dis. 2009 Oct 15;200(8):1279-88. doi: 10.1086/605896.

Gómez-Villafuertes R, del Puerto A, Díaz-Hernández M, Bustillo D, Díaz-Hernández JI, Huerta PG, Artalejo AR, Garrido JJ, Miras-Portugal MT. Ca2+/calmodulin-dependent kinase II signalling cascade mediates P2X7 receptor-dependent inhibition of neuritogenesis in neuroblastoma cells. FEBS J. 2009 Sep;276(18):5307-25. doi: 10.1111/j.1742-4658.2009.07228.x. Epub 2009 Aug 13.

Sánchez-Nogueiro J, Marín-García P, León D, León-Otegui M, Salas E, Gómez-Villafuertes R, Gualix J, Miras-Portugal MT. Axodendritic fibres of mouse cerebellar granule neurons exhibit a diversity of functional P2X receptors. Neurochem Int. 2009 Dec;55(7):671-82. doi: 10.1016/j.neuint.2009.06.009. Epub 2009 Jun 26.

Carrasquero LM, Delicado EG, Bustillo D, Gutiérrez-Martín Y, Artalejo AR, Miras-Portugal MT. P2X7 and P2Y13 purinergic receptors mediate intracellular calcium responses to BzATP in rat cerebellar astrocytes. J. Neurochem. 2009 Aug;110(3):879-89. doi: 10.1111/j.1471-4159.2009.06179.x. Epub 2009 May 18.

Gómez-Ramos A, Díaz-Hernández M, Rubio A, Díaz-Hernández JI, Miras-Portugal MT, Avila J. Characteristics and consequences of muscarinic receptor activation by tau protein. Eur Neuropsychopharmacol. 2009 Oct;19(10):708-17. doi: 10.1016/j.euroneuro.2009.04.006. Epub 2009 May 7.

Ortega F, Pérez-Sen R, Delicado EG, Miras-Portugal MT. P2X7 nucleotide receptor is coupled to GSK-3 inhibition and neuroprotection in cerebellar granule neurons. Neurotox Res. 2009 Apr;15(3):193-204. doi: 10.1007/s12640-009-9020-6. Epub 2009 Feb 24.

Díaz-Hernández M, Díez-Zaera M, Sánchez-Nogueiro J, Gómez-Villafuertes R, Canals JM, Alberch J, Miras-Portugal MT, Lucas JJ. Altered P2X7-receptor level and function in mouse models of Huntington's disease and therapeutic efficacy of antagonist administration. FASEB J. 2009 Jun;23(6):1893-906. doi: 10.1096/fj.08-122275. Epub 2009 Jan 26.

Díaz-Hernandez M, del Puerto A, Díaz-Hernandez JI, Diez-Zaera M, Lucas JJ, Garrido JJ, Miras-Portugal MT. Inhibition of the ATP-gated P2X7 receptor promotes axonal growth and branching in cultured hippocampal neurons. J Cell Sci. 2008 Nov 15;121(Pt 22):3717-28. doi: 10.1242/jcs.034082.

Gómez-Ramos A, Díaz-Hernández M, Rubio A, Miras-Portugal MT, Avila J. Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells. Mol Cell Neurosci. 2008 Apr;37(4):673-81. doi: 10.1016/j.mcn.2007.12.010. Epub 2007 Dec 15.

Marín-García P, Sánchez-Nogueiro J, Gómez-Villafuertes R, León D, Miras-Portugal MT. Synaptic terminals from mice midbrain exhibit functional P2X7 receptor. Neuroscience. 2008 Jan 24;151(2):361-73. Epub 2007 Nov 12.

Ortega F, Pérez-Sen R, Miras-Portugal MT. Gi-coupled P2Y-ADP receptor mediates GSK-3 phosphorylation and beta-catenin nuclear translocation in granule neurons. J Neurochem. 2008 Jan;104(1):62-73. Epub 2007 Nov 6.