.- J.I. Diaz-Hernandez, R. Gomez-Villafuertes, M. León-Otegui, L. Hontecillas-Prieto, A. del Puerto, J. L. Trejo, J. J. Lucas, J. J. Garrido, J. Gualix, M. T. Miras-Portugal, M. Diaz-Hernandez. In vivo P2X7R inhibition reduces amyloid plaques in Alzheimer Disease through GSK3beta and secretases. Neurobiology of Aging 2011, Nov 1. [Epub ahead of print]
.- Engel T, Gomez-Villafuertes R, Tanaka K, Mesuret G, Sanz-Rodriguez A, Garcia-Huerta P, Miras-Portugal MT, Henshall DC, Diaz-Hernandez M. Seizure suppression and neuroprotection during status epilepticus by targeting the purinergic P2X7 receptor in mice. FASEB journal 2012 26(4):1616-28 .
.- C. Tomás-Zapico, M. Diez Zaera, I. Ferrer, P. Gomez-Ramos, M. A. Morán, M. T. Miras-Portugal, M. Díaz-Hernández and J. J. Lucas. Alpha-synuclein accumulates in huntingtin inclusion but forms independent filaments and its deficiency attenuates early phenotype in a mouse model of Huntington´s disease. Human Molecular Genetic 2012, 21(3):495-510

-. A. del Puerto, J.I. Díaz-Hernández, M. Tapia, R. Gomez-Villafuertes, M. J. Benitez, J. Zhang, M.T. Miras-Portugal, F. Wandosell, M. Díaz-Hernández, J.J. Garrido. Coordinated action of ADP activated P2Y1 and P2Y13 receptors and ATP-gated P2X7 receptor modulate axonal elongation throughout regulation of adenylate cyclase 5. Journal of Cell Science. 2012, 125(Pt 1):176-88
.- Simón D, García-García E, Gómez-Ramos A, Falcón-Pérez JM, Díaz-Hernández M, Hernández F, Avila J. Tau Overexpression Results in Its Secretion via Membrane Vesicles. Neurodegener Disease 2012, 10(1-4):73-5.
.- León-Otegui M, Gómez-Villafuertes R, Díaz-Hernández JI, Díaz-Hernández M, Miras-Portugal MT, Gualix J. Opposite effects of P2X7 and P2Y(2) nucleotide receptors on a-secretase-dependent APP processing in Neuro-2a cells. FEBS Letters 2011, 585(14):2255-62 

.- C. Blázquez, A. Chiarlone, O. Sagredo, T. Aguado, M. R. Pazos, E. Resel, J. Palazuelos, B. Julien, M. Salazar, C. Börner, C. Benito, C. Carrasco, M. Diez-Zaera, P. Paoletti, M. Díaz-Hernández, M, Sendtner, J.J. Lucas, J. G. de Yébenes, G. Marsicano, K. Monory, B. Lutz, J. Romero, J, Alberch, S. Ginés, J. Kraus, J. Fernández-Ruiz, I. Galve-Roperh y M. Guzmán. Early loss of striatal cb1 cannabinoid receptors is critically involved in the pathogenesis of Huntington’s disease. BRAIN 2011, 134(Pt 1):119-36
.- Díez-Zaera M, Díaz-Hernández JI, Hernández–Álvarez E, Zimmermann H, Díaz-Hernández M* and Miras-Portugal MT*. Tissue nonspecfic alkaline phosphatase promotes axonal growth of hippocampal neurons. Molecular Biology of the Cell 2011, 22 (7), 1014-24 *Joint senior author.
.- Z. Ortega, M. Díaz-Hernández, C.J. Maynard, F. Hernández, N.P. Dantuma y J.J Lucas. Acute polyglutamine expression in inducible mouse model unravels ubiquitin/proteasome system impairment and permanent recovery due to aggregate formation. Journal of Neuroscience 2010, 30(10):3675-88.
.- M Díaz-Hernández, A Gómez-Ramos, A Rubio, R Gómez-Villafuertes, J R. Naranjo, M T Miras-Portugal, J Avila. Tissue non-specific alkaline phosphatase promotes the neurotoxicity effect of extracellular tau. Journal of Biological Chemistry 2010, 285:32539-48
.- A. Saavedra, J.M. García-martínez, X. Xifró, J.F. Torres-Peraza, J.M. Canals, M. Díaz-Hernández, J.J. Lucas, J. Alberch y E. Pérez-Navarro. PHLPP1 contributes to maintain the activation of the PI3k/Akt prosurvival pathway in Huntington’s disease striatum. Cell Death and Differentiation 2010, 17(2):324-35. 

.- X. Xifro,; A. Giralt,; A. Saavedra, J.M. Garcia-Martinez, M. Diaz-Hernandez, J.J Lucas, J. Alberch, E. Perez-Navarro. Reduced calcineurin protein levels and activity in exon-1 mouse models of Huntington's disease: role in excitotoxicity corresponding. Neurobiology of Disease 2009, 36(3):461-9.
.- R. Gómez-villafuertes, A del Puerto, M. Díaz-Hernández, D. Bustillo, J.I. Díaz-hernández, P.G. Huerta, A.R. Artalejo, J.J. Garrido, M.T. Miras-Portugal. Ca2+/calmodulin-dependent kinase ii signalling cascade mediates P2X7-dependent neurite outgrowth in neuroblastoma cells. FEBS Journal 2009, 276(18); 5307–5325.

.- C.J. Maynard, C. Böttcher, Z. Ortega, R. Smith, B.I. Florea, M. Díaz-Hernández, P. Brundin, H.S. Overkleeft, J.I. Li, J.J. Lucas y N.P. Dantuma. Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs in the absence of the global impaorment of the ubiquitin/proteasome system. PNAS 2009, 106(33):13986-91    

.- A. Gómez-Ramos, M. Díaz-Hernández¹, A. Rubio, J.I. Díaz-Hernández, M.T. Miras-Portugal y J. Avila. Characteristics and consequences of muscarinic receptor activation by tau protein. European Neurophycopharmacology 2009, 19, 708–717. ¹equally contributed

.- Díaz-Hernández M, Díez- Zaera M, Sánchez-Nogueiro J, Gómez-Villafuertes R, Canals JM, Alberch J, Miras-Portugal MT and Lucas JJ. Altered P2X7 receptor level and function in Huntington’s disease mouse models: therapeutic efficacy of antagonist administration FASEB Journal 2009, 23 (6):1893-1906
.- Díaz-Hernández M, del Puerto, A Diaz-Hernández J.I. , Diez-Zaera M., Lucas J.J., Garrido J.J. y Miras-Portugal M.T. Inhibition of the ATP-gated P2X7 receptor promotes axonal growth and branching in cultured hippocampal neurons. Journal of Cell Science 2008 15; 121:3717-28.
.- Gómez-Ramos A, Diaz-hernández M, Rubio A, Miras-Portugal M.T. y Avila J. Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells. Molecular and Cellular Neurosciences 2008. 37(4):673-81.